Endocrinology
New York"s Kendra"s Law to provide assisted outpatient treatment for people with severe mental illness is effective in a wide-range of measures, and provides long-lasting benefits the longer someone with a mental illness is in the program, a comprehensive independent evaluation conducted for the state by Duke University Medical School finds.
Two new specialist teams will be set up to improve diagnosis, care and support for people with eating disorders in Wales, Health Minister Edwina Hart officially announced.
-- The NPHS influenza surveillance scheme, which records reports of diagnoses of flu from more than 300 GP practices across Wales, shows low levels of influenza activity in all parts of Wales. Further detail can be found on the NPHS website: http://www.wales.nhs.uk/sites3/page.cfm?orgid=457&pid=38241
If you believe everything you read, "health and safety" is to blame for a lot of fun events being cancelled. Plastic duck races, ice cream toppings and even Morris Dancing have all allegedly fallen victim to excessive health and safety regulations.
An MS Society-funded study has highlighted the impact that MS has on partners" lives and demonstrates the need for support and services for partners of people with MS.
The Honourable Leona Aglukkaq, Minister of Health, yesterday welcomed more than 750 health professionals, researchers and indigenous representatives from across the world to the 14th International Congress on Circumpolar Health (ICCH-14) in Yellowknife, Northwest Territories.
Those who think extreme sports are all about risk-taking are missing the point, according to a QUT researcher. Eric Brymer, a lecturer from the School of Human Movement Studies in the Faculty of Health, has been researching whether the element of risk was an important factor among participants in "extreme" sports such as waterfall kayakers, mountain climbers, big wave surfers and B.A.S.E. jumpers.
Teva Pharmaceutical Industries Ltd. (NASDAQ: TEVA) announced that the U.S. Food and Drug Administration (FDA) has approved its New Drug Application (NDA) for Plan B® One-Step emergency contraception (levonorgestrel tablet, 1.5 mg). Now, with new Plan B® One-Step, women can help prevent an unintended pregnancy after unprotected sex or contraceptive failure with just one pill in one dose. The FDA is expanding over-the-counter (OTC) access to Plan B® One-Step for consumers age 17 or older; women younger than age 17 will require a prescription. The product will be available at licensed U.S. retail pharmacies within the next month.
The Alabama Department of Public Health has proposed a $650 civil penalty against
More than 5,600 Louisiana tobacco users received free medication last month to help overcome their addiction to tobacco. The initiative was part of a statewide promotion to assist with tobacco cessation by providing a month"s supply of nicotine replacement therapy patches to residents trying to quit tobacco products.
Scientists at the German Cancer Research Center Deutsches Krebsforschungszentrum (DKFZ) in Heidelberg, Germany, are using the enterprise analytics platform from TIBCO Software Inc. (NASDAQ: TIBX) for scientific research. This research includes looking at the mechanisms behind the causes of cancer, development of custom-tailored drugs, and understanding the types of cancer caused by infections.
Caesarean sections -- which are performed in 31% of births, up from 4.5% in 1965 -- often are considered an unnecessary risk and "an example of how the intensive and expensive U.S. brand of medicine has failed to deliver better results and may, in fact, be doing more harm than good," the Los Angeles Times reports. According to the Times, c-sections can increase a woman"s risk of complications, such as infection, blood clots and premature delivery. Even without complication, c-sections typically result in longer hospital stays and increased costs. Expenses related to c-section births account for 45% of the more than $79 billion in annual hospital charges that childbirth incurs in the U.S. annually. The average uncomplicated c-section costs about $4,500, which is about twice the cost for vaginal births. C-sections cost about $13,000 for privately insured patients. According to a 2008 report by Childbirth Connection, "The financial toll of maternity care on private (insurers)/employers and Medicaid/taxpayers is especially large." It also said, "Maternity care thus plays a considerable role in escalating health care costs, which increasingly threaten the financial stability of families, employers, and federal and state budgets." Addressing the Increase
Research published in the June 26, 2009 edition of Proceedings of National Academy of Sciences provides further evidence for novel roles of tRNA synthetases in disease, validating the therapeutic potential for aTyr Pharma"s new class of naturally occurring protein agents. The aminoacyl tRNA synthetases are universal and essential components of protein synthesis machinery found in all organisms, but human synthetases have naturally occurring resected variants with potent cell signaling activities that are vital to normal functioning of humans. aTyr Pharma"s proprietary product generating engine consists of these resected proteins (resectins) of human aminoacyl tRNA synthetases with cell signaling activities distinct from the protein synthesis activities. In this recently published study, a model of a human neuropathy was created in the fruit fly (Drosophila) by introducing mutations in the tyrosyl-tRNA synthetase which correspond to disease associated mutations in humans. These dominant mutations do not cause a loss in the protein synthesis activity, indicating that the neuropathy arises from distinct activities of this tRNA synthetase. This work provides further proof of noncanonical roles for tRNA synthetases in human disease.
The average time patients in Boston wait for an appointment to see a specialist has increased over the last five years to an average of 50 days and can be up to one year, despite the fact that the city has an "abundance" of specialists, according to a recent study, the Boston Globe reports. For the study, Merritt, Hawkins & Associates, a Texas-based consulting and physician recruiting firm, surveyed 1,162 physician offices in 15 metropolitan areas to try to re-create the situation of a new patient seeking a nonurgent appointment in five specialty areas -- cardiology, dermatology, family medicine, obstetrics-gynecology and orthopedic surgery. The average wait time in Boston is more than three weeks longer than any other city included in the study. The study determined that while Boston patients had the longest wait times for appointments to see dermatologists, ob-gyns and family practitioners, Dallas had the longest wait times to see orthopedic surgeons, followed by Boston. Miami, Minneapolis and San Diego all had longer wait times to see cardiologists than Boston.According to the study, while Boston patients have long faced delays, the problem may have been exacerbated by an increase in patients seeking care following the implementation of the 2006 Massachusetts health insurance law. While the study did not pinpoint a cause for longer wait times in Boston, the study"s authors wrote that the city"s experience "may signal what could happen nationally in the event that access to health care is expanded through health care reform."Brian Rossman, research director for Health Care for All, said the reason for long wait times also is because many specialists in Boston work for academic medical centers and do not see patients full time (Kowalczyk, Boston Globe, 5/15).
Nanostructured materials have garnered great interest worldwide due to their unique size-dependent properties for chemical, electronic, structural, medical and consumer applications.
The School Nutrition Association"s 2008 National School Lunch Week Campaign, "Vote for School Lunch - Presidential Edition," was honored by the American Society of Association Executives (ASAE) with a 2009 Summit Award. The award will be presented to SNA during the 10th Annual Summit Awards Dinner, September 29, 2009 at the National Building Museum in Washington, DC.
"I stood up and applauded for women everywhere when I heard the news" that the United Nations Human Rights Council, including the U.S., "recognized maternal death as a human rights issue," CARE President and CEO Helene Gayle writes in an Atlanta Journal-Constitution opinion piece. Gayle writes that governments for the past 15 years "have failed to meet the commitments made and targets set to reduce the more than half a million maternal deaths every year."According to Gayle, preventing maternal death "requires three well-coordinated actions: sustain political leadership, secure adequate res and strengthen health systems." She adds that the resolution "is a positive step" but that it is "only effective if it translates into action." She continues, "It"s great to see the Obama administration places women and girls high on the agenda," adding that many members of Congress also support these issues.Reducing maternal mortality "requires significant res," Gayle writes. She adds, "To be blunt, an estimated global commitment of $39 billion over 10 years is needed to make significant progress." Such a commitment would be "an investment in women, their families and the economic productivity of nations," according to Gayle."The cost of not investing is far greater," Gayle continues. She notes that women "do two-thirds of the world"s work and produce nearly 60% of the world"s food." In addition, "children who lose their mothers are 10 times more likely to die in childhood than children with mothers," and maternal and newborn deaths "represent an estimated annual loss of $15.5 billion in productivity," according to Gayle. "Clearly, other development goals cannot be met without healthy mothers," she adds.She continues that the "most tragic and infuriating point" is that the "death of a woman in childbirth is one of the most inexcusable deaths on earth." Because high maternal mortality is a "barometer of weak health systems, often reflecting the low status of women," strengthening health systems to improve maternal health will therefore enable the system to "address other health needs," Gayle writes. She adds that countries such as Bangladesh, Ethiopia and Peru have improved mortality rates "through four lifesaving programs: family planning, skilled and culturally sensitive care during pregnancy and childbirth, emergency care for complications and postpartum care."Gayle writes, "The U.S. can spearhead a comprehensive maternal health action plan and, by doing so, set an example for world leaders to join and invest in." She concludes, "The actions we take now can make maternal death a problem of the past and not one of our children"s future" (Gayle, Atlanta Journal-Constitution, 7/10).
HHS Secretary Kathleen Sebelius announced today that the department will commit $884 million to purchase additional supplies of two key ingredients for potential H1N1 vaccine to further prepare the nation for a potential resurgence of the 2009 H1N1 virus.
Alejandro Gutierrez, MD, is the third recipient of the ASH-AMFDP grant, an award designed to help increase the number of underrepresented minority scholars in the field of hematology, and will begin his research into the pathogenesis of T-cell acute lymphoblastic leukemia (T-ALL) this month. The award, the result of a partnership between the American Society of Hematology (ASH) and the Harold Amos Medical Faculty Development Program (AMFDP) of the Robert Wood Johnson Foundation, provides four years of support, including an annual stipend of up to $75,000 and an annual grant of more than $29,000 for research activities.
The American Society of Hematology (ASH), the world"s largest professional society of blood specialists, will honor six scientists who have made significant contributions to the understanding of hematologic diseases. These awards, including the newly created Ernest Beutler Lecture and Prize, will be presented at the 51st ASH Annual Meeting taking place December 5-8 in New Orleans.
House Democrats on Friday as part of a spending measure to fund the Departments of Labor and HHS for fiscal year 2010, "unveiled legislation to lift a ban on federal funding for needle-exchange programs, a shift to try to reduce [HIV infections] but one that will probably spark a fight," Reuters/Boston Globe reports (7/11). The ban has been included in the annual spending bill in previous years. House Appropriations Committee Chair David Obey (D-Wis.) said, "Scientific studies have documented that needle exchange programs, when implemented as part of a comprehensive prevention strategy, are an effective public health intervention for reducing [HIV] infections and do not promote drug use" (Reuters, Pelofsky, 7/10). "The move is in keeping with a pledge [President] Obama made during the primaries to remove the prohibition on such funding, although the ban was carried in his budget request this year," CQ Today reports (Wolfe, 7/10). However, "Republicans are girding for a fight over the ban and lawmakers could try to restore it as the legislation moves through the House during the next two weeks," according to Reuters (7/10). The bill also addresses sex education and "appears to continue Democrats" slow march away from funding abstinence-only sex education," CQ reports (7/10).
Going out like a brilliant flame is one way to get attention. If physicians could watch tumor cells committing a form of programmed suicide called apoptosis, a desired effect of workhorse cancer treatments such as chemotherapy and radiotherapy, they could more quickly pick the most effective treatment. Now scientists at the Stanford University School of Medicine have found a way to do just that, by lighting up cells as they die.
"I am stopping TB and controlling HIV" was the theme of an event marking World TB Day (24 March) in Uganda"s Masindi district. The Union Uganda Office participated in this event, which attracted representatives from both government and a wide variety of NGOs, as well as the public.
The beta-carotene in so-called "Golden Rice" converts to vitamin A in humans, according to researchers at Baylor College of Medicine and Tufts University in an article that appears in the current issue of the American Journal of Clinical Nutrition.
AMAG Pharmaceuticals, Inc. (NASDAQ:AMAG) announced that Feraheme ™ (ferumoxytol) Injection is now available for commercial sale in the United States. Feraheme is an intravenous (IV) iron replacement therapy for the treatment of iron deficiency anemia in adult patients with chronic kidney disease. Feraheme can provide patients with a 1 gram therapeutic course of iron in two 510 mg IV injections administered as quickly as 17 seconds each, within one week. Feraheme was approved by the U.S. Food and Drug Administration on June 30, 2009.
New research from the Stanford University School of Medicine and Stanford Hospital & Clinics suggests that the use of a dietary supplement after Roux-en-Y gastric bypass surgery can help obese patients to more quickly lose weight and to avoid deficiency of a critical B vitamin.
Undocumented people live in a shadowy world of high fear and stress -- fear of deportation and stress brought on lack of economic, linguistic and educational res.
Previous studies have found that postmenopausal women who have taken a combined estrogen and progestin hormone replacement therapy have increased their risk of developing progestin-accelerated breast tumors. Now, University of Missouri researchers have found that curcumin, a popular Indian spice derived from the turmeric root, could reduce the cancer risk for women after exposure to hormone replacement therapy.
Scientists have shown that E. coli - one of the best known and extensively studied organisms in the world - remains an enigma that may hold the key to human diseases, such as cancer.
A study by scientists at Penn State provides new information about the genes that are involved in a mammal"s early brain development, including those that contribute to neurological disorders. The study is the first to use high-throughput sequencing to uncover active genes in developing brains, and it is likely the best evidence thus far for the activity in the brain of such a large number of genes. The research results one day could lead to the development of drugs or gene therapies that treat neurological disorders such as autism and mental retardation. The research, which was led by Distinguished Professor of Biology Hong Ma and Associate Professor of Biology Gong Chen, will be published online in the Early Edition of the Proceedings of the National Academy of Sciences sometime during the week of 13 July 2009.
Elsevier has announced the launch of the official version of BrainNavigator, a neuroscience research tool developed in collaboration with the Allen Institute for Brain Science and under the editorship of Professor George Paxinos and Charles Watson, Prince of Wales Medical Research Institute, Sydney. After unveiling the prototype version at the Society for Neuroscience"s Neuroscience 2008 tradeshow last November, the rodent brain version is now available at http://www.brainnav.com.
Results from two large studies using DHA, an omega 3 fatty acid, were
A new research study from Scripps Health provides previously unknown genetic clues into how cancerous tumors are formed in the human breast, brain and colorectal system. The findings by researchers at Scripps Translational Science Institute (STSI) will be published in the September 2009 edition of the journal Genome Research.
CytRx Corporation (NASDAQ: CYTR), a biopharmaceutical research and development company engaged in the development of high-value human therapeutics, today announced that its investigational cancer drug INNO-206 caused a dramatic destruction of implanted tumors in an experimental animal model of breast cancer, performing considerably better than the broadly used and generally effective chemotherapeutic drug doxorubicin. In addition to improved efficacy in this animal trial, INNO-206 was comparable in toxicity with doxorubicin based on animal body-weight loss.
The American College of Physicians (ACP) joined with two other physician groups to offer strong support for the Comparative Effectiveness Research (CER) provisions included in the Tri-Committee health reform bill about to be considered in the House. The Tri-Committee, which unveiled its proposed legislation on June 19, is made up of the House Ways and Means, Energy and Commerce, and Education and Labor Committees.
The following statistics were released today by the Department of Health:
New data show that Medicare beneficiaries registered to use My Health Manager, Kaiser Permanente"s personal health record, are overwhelmingly satisfied with using the Internet to manage their health care online. Results from the recent Kaiser Permanente survey examining Web site usage and Medicare beneficiary satisfaction were presented today at the World Health Care Congress" 5th Annual Leadership Summit on Medicare in Washington, D.C.
Research currently underway at The Cancer Institute of New Jersey (CINJ) and CINJ-Hamilton, which may unlock the mysteries of why some women develop breast cancer at an earlier age than others, has been expanded to include more healthy volunteers than previously sought. CINJ is a Center of Excellence of UMDNJ-Robert Wood Johnson Medical School.
The New York City-based advocacy group Community Service Society recently released a report that found racial health disparities among state health plan beneficiaries, New York Times" "City Room" reports. The report urged state officials to close the gaps. The roughly 20 health plans that contract with the state public health programs to provide health insurance to low-income residents are required to break down health indicators by race. Using data from the New York State Department of Health, researchers found that out of 12 measures the state uses in quality assurance, including dental visits, asthma management, mammography and almost all diabetes indicators:
Blacks and others with darker skin might be at greater risk for tobacco addiction than whites and those with lighter skin because the greater the amount of melanin, the coloring pigment in skin, the more nicotine appears to be stored, according to preliminary findings published in the journal Pharmacology, Biochemistry and Behavior, the New York Times reports. For the study, lead researcher Gary King, a professor of biobehavioral health at Pennsylvania State University, looked at 150 black smokers and measured their levels of melanin and cotinine, a byproduct of nicotine. They also surveyed the participants to determine the level of their smoking habit. Those with the most melanin were found to smoke the most and have the most cotinine in their system. They also had the highest level of dependence on tobacco. The findings might indicate why some people are more affected by nicotine than others, according to the study (Nagourney, New York Times, 5/19).
The eyes may be the window into the soul, but they may also contain important medical information. According to new research presented at the American Thoracic Society"s 105th International Conference in San Diego on May 19, patients with diabetes who have retinopathy should also be screened for obstructive sleep apnea (OSA).
New figures published show A&E departments in England have met the
"An unprecedented effort to computerize the nation"s hospitals and physician offices could be the key to reducing crippling health care costs - or a giveaway to technology vendors whose sales will be subsidized by taxpayers," the Dallas Morning News reports. The $45 billion, stimulus-funded effort in question could help reduce costs by cutting into the country"s $37.6 billion in medical errors each year, for instance. But, if requirements for providers seeking stimulus funding are too strict, the program could turn into "a bonanza for software vendors."
There were 839 reported cases of HIV/AIDS in Alabama in 2008, and of those 122 were reported in Montgomery County, which had the highest number in the state per capita, the Montgomery Advertiser reports. Black residents comprised 70 percent of all HIV/AIDS cases in Alabama reported that year. Poverty, lack of transportation to health services, not knowing a partner"s status and not getting tested are cited as factors contributing to the greater risk for HIV among blacks in the state, according to the Advertiser. Jane Cheeks, director of HIV/AIDS programs for the Alabama Department of Public Health, said, "The more we test, the more we find," adding, "But we"re hoping we can lower the infection rate." She also said, "In 2007, we got a pretty significant increase in funding and we were able to provide more services and give more testing." In addition to administering HIV tests, the "state educates the public through public service announcements and rolling billboards on the sides of 18-wheelers, which give people toll-free numbers to call" for information, the article states (Klass, 7/11).
Passport Health of Massachusetts, specialists in vaccinations against dread diseases faced by international travelers, is concerned that eastern New England"s wettest spring and early summer in decades can be more deadly than usual.
"Secretary of State Hillary Clinton said Monday she is frustrated over the failure" to name a new head of the USAID, despite it being a priority for the administration, AFP/Google.com reports. "Clinton, addressing USAID staff who asked why there was no administrator and deputy six months into President Barack Obama"s administration, complained about what she called an increasingly burdensome vetting process," the news service writes (7/13).
"Swiss drug company Novartis AG and the Institute for OneWorld Health, a nonprofit group, will announce this week a partnership to discover drugs for a type of diarrhea that kills about 1.6 million children each year in the developing world," the Wall Street Journal reports.
Four members of the Medical Research Council community were recognised for their contribution to science by the Royal Society.
Boehringer Ingelheim and AmeriCares Free Clinics announced the opening of a new, expanded clinic in Danbury to serve the medical needs of the working poor at a time when demand for such services is higher than ever due to economic pressures.
People with mental health problems could find themselves without adequate help and support under proposals set out in today"s green paper on adult social care, warns leading mental health charity Rethink.
In response to the inquiry report into "Was the NHS Plan really a blueprint for the NHS - 10 years on?" released by the All Party Parliamentary Group Primary Care & Public Health today. Mubeen Bhutta Policy Manager at the British Heart Foundation said:
Endothelial progenitor cells may play a role in the start and progression of metastatic disease in children with cancer, according to study results published in Clinical Cancer Research, a journal of the American Association for Cancer Research.
Children of mothers who smoked during pregnancy and their early childhood years may be predisposed to take up smoking as teens and young adults, compounding the physical damage they sustained from the smoke exposure.
Results of a survey published in the July issue of the Journal of the American College of Surgeons show that a large subset of surgical residents consider duty hour regulations (DHR) a significant barrier to their surgical education and express a desire for flexibility to work longer hours than current restrictions allow.
A significantly more accurate* way of calculating the dosimetry of cancer treatments will be introduced by Varian Medical Systems (NYSE: VAR) at the GEC-ESTRO exhibition in Porto, Portgual, on May 14-16. BrachyVision™ Acuros™ enables clinicians to rapidly calculate patient doses for brachytherapy treatments (a form of radiotherapy) with an extremely high level of accuracy.
New data show that Medicare beneficiaries registered to use My Health Manager, Kaiser Permanente"s personal health record, are overwhelmingly satisfied with using the Internet to manage their health care online. Results from the recent Kaiser Permanente survey examining Web site usage and Medicare beneficiary satisfaction were presented today at the World Health Care Congress" 5th Annual Leadership Summit on Medicare in Washington, D.C.
The following are helpful tips to pet owners offered by veterinarians at Colorado State University?s Veterinary Teaching Hospital. The paragraphs can be used alone as filler or in a group as a set of tips. If you need additional information, please contact Dell Rae Moellenberg at 970-491-6009 or DellRae.Moellenberg@colostate.edu. If you?d like to attribute the information, please attribute it to Colorado State University?s College of Veterinary Medicine and Biomedical Sciences.
High-resolution comparative genomic hybridization (CGH) has rapidly emerged as the method of choice for molecular cytogenetic detection and characterization of chromosomal abnormalities associated with mental retardation, cancer, and other complex phenotypes. In two recent studies published in the Journal of Medical Genetics (1, 2), high-resolution NimbleGen CGH arrays were used to further characterize two recently identified genomic disorders (3, 4).
Memory lapses that occur with normal aging are a of worry for many who fear Alzheimer"s disease. Now a new Mayo Clinic-led study published in the July 16 issue of the New England Journal of Medicine suggests that the carriers of a common genetic risk factor for Alzheimer"s disease begin to have memory declines in their mid-50s, far earlier than previously thought.
Diabetes patients taking NovoLog((R)) (insulin aspart [rDNA origin] injection) can now use the insulin in their pump for up to six days following the U.S. Food and Drug Administration (FDA) approval of a labeling change, diabetes care company Novo Nordisk announced today.(1) The previous label allowed for NovoLog((R)) to be stored in the pump reservoir for two days. This makes NovoLog((R)) the first and only rapid-acting insulin with this extended in-use time.
Legislation protecting patients from the practice of health insurers and health plans canceling their coverage when they get seriously ill today passed the Senate Judiciary Committee.
Basilea Pharmaceutica Ltd. (SWISS: BSLN) announces that the National Institute for Health and Clinical Excellence (NICE) issued the Final Appraisal Determination (FAD) recommending the use of Toctino® (alitretinoin) within its licensed indication, as a treatment option for adults with severe chronic hand eczema that has not responded to potent topical corticosteroids.
Supreme Court nominee Sonia Sotomayor would be the sixth Roman Catholic currently on the court if she is confirmed, but there have been no more than "a few scattered references to this fact," Wall Street Journal columnist William McGurn writes. He continues that "for the most part the judge"s religion has been greeted, as a USA Today headline put it, with a "yawn."" McGurn adds, "How different from just a few years ago," when Catholics Justice Samuel Alito and Chief Justice John Roberts were nominated by former President George W. Bush.According to McGurn, when Alito was a Supreme Court nominee, "talk was about the "fifth Catholic" on the bench." He adds that Feminist Majority Foundation President Eleanor Smeal "complained that "with Alito, the majority of the court would be Roman Catholics."" McGurn writes that prior to the confirmation hearings for Chief Justice John Roberts, the Los Angeles Times "ran a piece headlined, "Wife of Nominee Holds Strong Antiabortion Views."" According to the Times, Roberts" wife worked for Feminists for Life, and the paper "characterized [her] as an "extremely, extremely devout Catholic,"" McGurn writes."It"s possible, of course, that Democrats and their allies in the media and activist community no longer regard Catholics with the suspicion they did back when ... Bush"s nominees were up for consideration," according to McGurn. "More likely, the relatively soft reaction to Ms. Sotomayor"s Catholicism is because of a calculation that when it comes to hot-button issues such as abortion or gay marriage, she doesn"t really believe what her church teaches," he writes.McGurn continues that if the "indifference" to "Sotomayor"s Catholicism were truly a sign of a new respect for the "no religious test" provisions of the Constitution, that would be something to celebrate." He concludes, "But in the unlikely case that this "wise Latina" ever comes to see the legal wisdom of overturning [Roe v. Wade] and returning abortion to the democratic process, we"ll be reading a very different story" (McGurn, Wall Street Journal, 7/14).
The winner of the chilli cook-off, usually has a key secret ingredient, which is hard to identify. Similarly, many diseases have crucial proteins, which change the dynamics of cells from benign to deadly. New findings from an international collaboration, involving McGill University, the Research Institute of the McGill University Health Centre (MUHC) and the Human Proteome Organisation (HUPO) just made identifying these changes one step easier. Their findings published in Nature Methods, show how to improve protein analysis to tease out relevant potential disease-causing molecules.
"A veteran California lawmaker with ties to the biotechnology industry said she thinks her proposal to protect brand-name biologic makers has enough support to carry in the House Energy and Commerce Committee," Dow Jones Newswires/Wall Street Journal reports. The proposal, by Rep. Anna Eshoo, D-Calif., would protect brand-name biologic products from competition for 12 years. A similar proposal cleared the Senate health committee earlier this week.
The Sioux Falls Argus Leader reports: "It might be only a footnote in health care reform this year, or perhaps a consolation prize. Either way, South Dakota ranks among the cheapest states in the nation for doing business through Medicare. The state is No. 47 with expenses averaging $6,253 for each person who uses the federal benefit to pay for health care. The U.S. average is $8,304. Officials attributed South Dakota"s results to local efficiencies and preventive health, and hope the good score might earn the state some benefit in proposed reforms. So far it hasn"t worked out that way, with Medicare cuts at this point appearing to apply evenly to all states. But researcher Elliott Fisher of the Dartmouth Institute for Health Policy and Clinical Practice, says the gap should be a tool in the debate as the government looks for ways to pay for reform."
A 9-1-1 For Health Care Reform: Send Leadership Now Washington Post
NPR reports on President Obama"s "broad global health strategy," which would increase the amount of funding for family planning, maternal and child health programs to about a "half billion dollars" next year. According to NPR, "the U.S. has committed $230 million [over the next five years] directly to health in Afghanistan, whose government has already built 2,000 health facilities since the collapse of the Taliban regime" (Wilson, 7/15).
As lawmakers debate how to pay for an overhaul of the nation"s health care system, a new report from The Commonwealth Fund projects that including both private and public insurance choices in a new insurance exchange would save the United States as much as $265 billion in administrative costs from 2010 to 2020. Congressional leaders are attempting to keep 10-year federal budget costs of health care reform legislation under $1 trillion.
Animas Corporation announcedthe approval of its OneTouch® Ping™ Glucose Management System by Health Canada. OneTouch Ping is the first full-feature insulin pump that wirelessly communicates with a blood glucose meter-remote. Using the OneTouch Ping meter-remote, a person can calculate insulin doses and opt to wirelessly instruct the pump to deliver them without touching the pump at all, giving patients more freedom and flexibility in using their insulin pump.
When we are feeling blue we are told to count our blessings, but according to a study recently published in Psychological Science, counting our money might be a more useful activity. Psychologists Xinyue Zhou, Sun Yat-Sen University, Kathleen D. Vohs, University of Minnesota, and Roy F. Baumeister, Florida State University, investigated the psychological, physical and social impact of money.
NHS clinical teams will have access to data showing their performance against a set of more than 200 indicators of high quality care in the NHS in one place. It is the next phase in the drive to help NHS professionals improve the quality of care they deliver to patients, and will also support providers and commissioners of NHS services.
Scientists at Duke University and the University of North Carolina have devised a chemical technique that promises to allow neuroscientists to discover the function of any population of neurons in an animal brain, and provide clues to treating and preventing brain disease.
Researchers from Boston University School of Medicine (BUSM) have shown that disclosing genetic risk information to adult children of patients with Alzheimer"s disease (AD) who request this information does not result in significant short-term psychological distress. The report from the REVEAL Study*, which appears in the July 16 issue of the New England Journal of Medicine, is the first randomized trial to disclose to participants whether or not they carried the íµ4 variant of the APOE gene, a variant that has been found to increase the risk of developing AD. The study demonstrated that test-related distress was reduced among those who learned that they were APOE íµ4 negative, and was only transiently increased among those who learned they were APOE íµ4 positive. The study also showed that persons with high levels of emotional distress before undergoing genetic testing were more likely to have emotional difficulties after disclosure.
The Council for Quality Respiratory Care (CQRC), a coalition of leading home oxygen therapy providers and manufacturers who provide care and services to chronically ill home oxygen patients, expressed strong support for the Medicare Home Oxygen Therapy Act of 2009 (H.R. 3220), legislation that offers a thoughtful, comprehensive approach to reforming the Medicare home oxygen benefit and protects the care needs of the nation"s home oxygen beneficiaries.
For the first time UK scientists have shown what the food poisoning bug Salmonella feeds on to survive as it causes infection: glucose.
Leading medical researchers from Australia"s George Institute for International Health are surprised by recent statements made by a Western Australian Member of Parliament, Hon. Carol Anne Martin MLA, who is calling for the removal of the alcohol restrictions in the Kimberley towns of Halls Creek and Fitzroy Crossing. The George Institute considers these statements a disappointing response to the positive community impacts of the alcohol restriction.
Ask middle-school students if they are popular or make friends easily, they likely will depend on social comparisons with their peers for an answer. Such reliance on the perceived opinions of others, or reflected self-appraisals, has long been assumed, but new evidence supporting this claim has now been found in the teen brain.
Obesity -- that never-ending "battle of the bulge"-- dates back to the Stone Age and yet is emerging today as a modern health epidemic. While its root cause is as simple as calories consumed versus calories burned, it"s cure is knotted somewhere in a complex web of biology, psychology and culture.
As life expectancy increases in developed economies, the healthcare industry is preparing for a number of new challenges as well as opportunities. A longer life span is expected to translate to a growing number of patients diagnosed with chronic conditions. To counteract the financial and medical infrastructure implications of this trend, pressure from the public sector and managed care organizations will place a premium on therapeutic self-administration, an expectation that is creating an increased interest in routes of administration that are patient-friendly and cost-effective. Pharma company decision makers have come to the realization that for many products, success no longer only depends on the medication itself but also on achieving a consumer-compatible form of packaging and application.
In a Phase III study, TIP, an inhaled investigational formulation of tobramycin, improved lung function (as measured by FEV1) in cystic fibrosis patients with Pseudomonas aeruginosa (Pa) infection, compared to placebo. The data, presented today at the American Thoracic Society (ATS) 2009 International Conference in San Diego, also demonstrated, with respect to secondary endpoints, that TIP decreased sputum Pa density, hospitalization and other antibiotic use in these patients versus placebo.
The Institute for OneWorld Health, the US-based non-profit pharmaceutical company that develops drugs for people with neglected infectious diseases in the developing world, today announced that it has launched a collaboration with global pharmaceutical leader Novartis to discover and develop a novel therapy for secretory diarrhea, a deadly disease that kills more than 1.6 million children in the developing world each year.
Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, announces it has received Fast Track designation from the U.S. Food and Drug Administration (FDA) for velaglucerase alfa, its enzyme replacement therapy in development for the treatment of Type I Gaucher disease. Shire is working with the FDA to determine subsequent steps and timing for the filing of its NDA.
The Lewin Group today released a new report assessing the financial impact and administrative burden that out-of-network claims pose in Medicaid managed care. The authors of the report recommend a federally mandated payment standard for Medicaid health plans similar to that used in the Medicare Advantage managed care program.
Dr. Zsuzsanna Nagy of the University of Birmingham presented data from a clinical study, funded by Cytox Limited, demonstrating that a simple blood-based biomarker discriminated between patients with Alzheimer"s disease (AD) and control subjects. The findings were statistically highly significant, and the test discriminated between the two groups with 80% sensitivity and 80% specificity. The results also showed that 40% of the mild cognitive impairment (MCI) patients tested had the same test results as AD patients. Follow up study of MCI patients enrolled in an earlier study found that the test allowed early identification of those MCI patients who later developed dementia. The results were presented at the 2009 Alzheimer"s Association International Conference on Alzheimer"s Disease (ICAD 2009), held in Vienna, Austria.
A recently identified gene allows immune cells to start the self-destructive processes thought to underlie autoimmune diseases such as multiple sclerosis (MS) and rheumatoid arthritis, researchers at Washington University School of Medicine in St. Louis have found.
Advances in neonatal care enable two-thirds of premature babies born with respiratory problems to be ready for school at an appropriate age, but those living in poverty are far less likely to be ready on time than their better-off peers, researchers from the University of Chicago Medical Center report in the July issue of the journal Pediatrics.
Americans are unsure that a healthcare reform bill introduced this week is the solution to problems with the U.S. healthcare system, according to a poll created and commissioned by a public policy expert at The University of Texas Health Science Center at Houston.
The repeal of the federal speed control law in 1995 has resulted in an increase in road fatalities and injuries, according to researchers at the University of Illinois at Chicago School of Public Health.
Researchers at the University of Rochester Medical Center have found a way to block the genetic flaw at the heart of a common form of muscular dystrophy. The results of the study, which were published in the journal Science, could pave the way for new therapies that essentially reverse the symptoms of the disease.
With debate underway in the House Education and Labor Committee today on the sweeping healthcare reform bill in that body, the nation"s largest organization of registered nurses today called on Committee Chair George Miller to support a critical amendment that would enable individual states to go a step farther and adopt single-payer, Medicare-for-All style reforms.
In President Obama"s push for health reform, "new fault lines are opening up everywhere you look. Liberals are worried that Obama is going squishy on including a strong, government-run "public option" among the health-care choices available to Americans. Conservatives are warning that the legislation won"t do enough to control health costs. Rural lawmakers are complaining that proposed Medicare cuts will fall too hard on their states," TIME reports. "And those are just the arguments going on among the Democrats. It"s all a sign that the season for hard decisions has arrived. Obama continues to project an air of confidence about the most audacious undertaking of his presidency" (Tumulty, 7/16).
"President Obama"s ambitious drive to overhaul the nation"s $2.3 trillion health-care system cleared a key Senate committee yesterday. But the administration was promptly buffeted by criticism from some of the industry players and moderate Democrats it has courted for months, calling into question the prospects for a bipartisan landmark bill," The Washington Post reports. This is the "the first time in 15 years a congressional panel has endorsed coverage for all. ň€¦ But the 13 to 10 party-line vote, after rancorous comments by the top Republican on the committee, underscored the mounting tensions in Congress and the country over the president"s signature item. From one end of Pennsylvania Avenue to the other, lawmakers, lobbyists and the president himself all moved quickly to position themselves for the intensifying battle."
"This is Year 20 for America"s Best Hospitals, a tool for patients who need medical sophistication that most facilities are unable to provide," reports U.S. News and World Report. The magazine ranked hospitals based on how well they did in "complex and demanding situations" such as "replacing an 85-year-old"s heart valve, diagnosing and treating a spinal tumor, and dealing with inflammatory bowel disease." Out of a total 4,861 hospitals analyzed, "Only 174 hospitals scored high enough to be ranked in even one of the 16 specialties. And of these, just 21 qualified for [the] Honor Roll by ranking at or near the top in at least six specialties." The ranking list includes the 50 highest scoring hospitals (Comarow, 7/15).
The American Nurses Association (ANA), which represents the interests of the nation"s 2.9 million registered nurses, is joining forces with the Texas Nurses Association (TNA) to strongly criticize the recent indictment and prosecution of two registered nurses in Winkler County, Texas, for reporting to the Texas Medical Board their concerns about a physician"s standard of practice at the Winkler County Memorial Hospital in Kermit, Texas. ANA and TNA are gravely concerned about the chilling effect the county"s actions could have on future nurse "whistle blowers" who advocate for their patients in the nation"s hospitals. An initial hearing on the nurses" motions to dismiss the case was held July 15 in the Winkler County Courthouse but no rulings were made on any of the motions.
"A hospital that serves thousands of indigent Massachusetts residents sued the state on Wednesday, charging that its costly universal health care law is forcing the hospital to cover too much of the expense of caring for the poor," according to the New York Times.
The health ministers of six South American countries gathered in Buenos Aires, Argentina, on Wednesday to "coordinate defenses against" the H1N1 (swine flu) virus which has killed nearly 200 people in the region," the AFP/Google.com reports. Ministers from Argentina, Bolivia, Brazil, Chile, Paraguay and Uruguay used the meeting to voice concern over the rapid spread of the H1N1 virus in their countries, which are now in the southern hemisphere"s winter months, and discuss ways to share supplies to help prevent the spread of the virus. The article includes the individual strategies being taken by some South American countries (7/15).
Researchers have sequenced the genomes of two parasites that cause bilharzia or schistosomiasis - a disease transmitted by water-borne snails that affects more than 200 million people worldwide - "revealing potential weaknesses that could be exploited by drug developers," Nature reports (Smith, 7/15).
IRIN examines the efforts of the Geneva-based Foundation for Innovative New Diagnostics (FIND) to develop less costly surveillance equipment to improve the ability to detect the parasitic disease trypanosomiasis (sleeping sickness) in endemic countries. Though "trypanosomiasis can be cured within a week of hospitalization," left undetected, the disease advances, making it treatable only by medication that "can be toxic in up to 10 percent of patients," according to Joseph Ndung"u, head of FIND"s trypanosomiasis program.
The Amarillo, Texas City Commission on Tuesday received a grant from the Texas Department of State Health Services, of which $51,636 will be used for HIV surveillance activities across the Texas Panhandle Region, NewsChannel10.com reports. According to NewsChannel10.com, the "grant supports the investigation, review and reporting of HIV/AIDS positive cases to the State Health Department" (Lemmons, 7/15).
US researchers have discovered the molecular mechanisms by which the human body metabolizes selenium, a trace element that plays an essential
As part of a series about Americans" response to the H1N1 flu outbreak, the Harvard Opinion Research Program at the Harvard School of Public Health is releasing a national poll that focuses on Americans" views and concerns about the potential for a more severe outbreak of Influenza A (H1N1) in the fall or winter. The polling was done June 22-28, 2009.
Consumers may be able to eat longer-lasting, potentially healthier fish fillets if research at Oregon State University makes its way to the supermarket.
The Health and Safety Executive (HSE) is warning gas engineers of the significant costs of failing to register with the Gas Safe Register following the prosecution an unregistered gas engineer from Warwick.
An upcoming G&D paper reveals how two specific matrix metalloproteinase (MMP) proteins contribute to bone metastasis in advanced breast cancer - lending important new insight into the design of clinically useful small molecule inhibitors.
A UQ institute has joined forces with a leading American university to work on research to change the way we live.
Every 30 seconds a person somewhere in the world loses a lower limb to amputation due to diabetic foot disease.
Mental health diagnoses increased substantially after the start of the Iraq War among specific subgroups of returned veterans entering Veterans" Administration (VA) health care, reports a new study.
A new study points to evidence that the 1995 repeal of federal limit controls resulted in an increase of road fatalities and injuries.
It"s a word that"s been around since the days of the Truman presidency. But a patient looking up "physiatry" would find nothing in the dictionary.
The Pennsylvania Insurance Department will conduct examinations of the state"s four Blue Cross and Blue Shield insurance companies, Blue Cross of Northeastern Pennsylvania, Capital BlueCross, Highmark, Inc. and Independence Blue Cross, to determine if any of them were engaged in anti-competitive or unfair trade practices in violation of the law, Insurance Commissioner Joel Ario announced today.
Researchers from Weill Cornell Medical College have published results showing that a new contraceptive device may also effectively block the transmission of the HIV virus. Findings show that the device prevents infection by the HIV virus in laboratory testing. The promising results are published in the most recent issue of the journal AIDS.
Rabies is a virus that occurs in mammals and infects the central nervous system; the disease can cause death in humans if it is not treated. Nearly 90 percent of cases occur in wild animals (raccoons, bats, foxes etc.); less than 10% of cases occur in domestic animals like dogs or cats. Humans usually become infected when they are bitten by an infected animal.
Adults between the ages of 34 and 56 are at a greater risk of dying from poisonings than from motor vehicle accidents, according to a new report from the CDC.
Bone fractures might heal faster if the patient is injected with medications. This is the outcome of a unique study of 102 women with wrist fractures.
People who can speak two languages are more adept at learning a new foreign language than their monolingual counterparts, according to research conducted at Northwestern University. And their bilingual advantage persists even when the new language they study is completely different from the languages they already know.
Teens who drink heavily are more likely than their peers to have behavioural and attention problems and suffer from anxiety and depression, a team led by researchers from the Norwegian University of Science and Technology (NTNU) has reported.
The House on Thursday voted 219-208 to approve a fiscal year 2010 Financial Services spending bill (HR 3170), which includes a provision reversing a long-standing congressional ban on allowing Washington, D.C., to use locally derived revenue to fund or subsidize abortion services, the AP/Washington Post reports (AP/Washington Post, 7/17). The measure maintains a ban on using federal funds for abortion services in the district.According to CQ Today, Thursday"s vote followed a "lengthy and sometimes heated debate" marked by Republicans and some moderate Democrats" dissatisfaction with a rule restricting amendments. The House voted 216-213 to approve the rule, which allowed 17 amendments but excluded any on the D.C. abortion funding provision (Clarke, CQ Today, 7/16).
One thing that "has been conspicuously absent" from the confirmation hearings for Supreme Court nominee Sonia Sotomayor is "substance," Jonathan Turley, the Shapiro Professor of Public Interest Law at George Washington University, writes in a USA Today opinion piece. According to Turley, "The vast majority of questions and answers remained on a shallow and predictable level where Sotomayor did little more than describe current doctrines and case law -- avoiding disclosures of her own views." He continues, "What is most striking is how Sotomayor"s statements were virtually identical to both her conservative and liberal predecessors," including her comments that Roe v. Wade and Planned Parenthood v. Casey are "the precedent of the court."Turley writes, "The content-light character in these hearings is largely the product of the "Ginsburg rule" -- named after Justice Ruth Bader Ginsburg, who refused to answer questions in her 1993 confirmation hearing about any case or matter upon which she might later vote." According to Turley, "Later nominees for both parties have relied on the Ginsburg rule to turn the hearings into prolonged photo-ops for senators, who largely ask wafer-thin questions to solicit largely scripted answers." The rule "allows nominees to get by with meaningless sound bites that promise to respect precedent, the Framers [of the Constitution] and collegiality in general," he adds. Furthermore, it "tells the public nothing about a nominee"s philosophy or purpose before giving her life tenure on the world"s most powerful court," Turley writes.According to Turley, there is a "simple solution to returning substance to the confirmation process: End the Ginsburg rule by insisting that nominees answer questions about their specific views on constitutional rights." Although "the current system works well for presidents, nominees and senators," it "does little for the public or the system of justice," he writes (Turley, USA Today, 7/16).
Hospitals across Canada are seeking ways to free up beds. University of Alberta researcher Donna Wilson has a suggestion: people should be encouraged to die at home rather than in hospital.
Why The Cheers? The Washington Post
The Department of Justice on Thursday said that it is a violation of the Americans with Disabilities Act to bar people -- such as barbers, masseuses, and home health care aides -- from receiving professional licenses or training at occupational schools because they have HIV or AIDS, the AP/Los Angeles Times reports. Some states, for example, require that cosmetologists be free of communicable diseases. "The government says that type of regulation is outdated and was not intended to bar people with HIV. The original goal of such a rule was to prevent the spread of tuberculosis and other diseases, not prevent people with [HIV] from working in certain fields," according to the AP/Times. Furthermore, "The Supreme Court has found people with AIDS or HIV are covered under the law barring discrimination against people with disabilities," the article states (7/16).
NHS South West Essex has launched an ambitious mobile MMR immunisation programme to improve vaccination rates among 20,000 at risk children.
As a result of the scientific advances and medical innovations made in the twentieth century, the United States today occupies an established and unchallenged leading role in the field of surgery. Renowned surgeon Seymour I. Schwartz, MD, gives a sweeping history of American surgical practice in "Gifted Hands: America"s Most Significant Contributions To Surgery" (Prometheus Books). He describes how surgery in the United States has advanced from the comparatively crude practices of pioneering physicians in the pre-Columbian and colonial eras to its current level of preeminence in scientific surgery today.
TECNALIA CorporaciĂön TecnolĂögica and the Valencia Institute for Biomechanics (IBV) have designed made-to-measure solutions to improve adaptation to replacements for amputated legs - the prime objective of the new health biomaterials project, FABIO, financed by the Ministry of Industry, Trade and Tourism.
Experts estimate that over 24 million people worldwide suffer from dementia, and many of these people live in low- and middle-income countries. Recently, there has been growing interest in whether dietary factors, particularly oily fish and meat, might influence the onset and/or severity of dementia. Oily fish are rich in omega-3 long-chain polyunsaturated fatty acids, which some studies suggest are positively related to cognitive function in later life. Conversely, there is a suggestion from some studies that increased meat consumption may be related to cognitive decline. To examine this, a group of international researchers studied older people in 7 middle- to low-income countries. You can read the results of their study in the August 2009 issue of the American Journal of Clinical Nutrition.
To improve access to highly specialized care and to further its commitment to patients suffering from spine-related disorders, Alvarado Hospital has opened the Advanced Spine Institute & Minimally Invasive Spine Center, a multi-specialty "one-stop" center dedicated to providing world-class care to patients with back, neck and complex spinal problems.
The prevalence of heart disease and certain key risk factors - hypertension, diabetes, and obesity - are increasing in all age groups and most income groups in Canada found a new study published in CMAJ (Canadian Medical Association Journal) http://www.cmaj.ca/press/cmaj081629.pdf. This study, which looked at national data from 1994 to 2005, encompassed people aged 12 years and older sampling from Canadians of all socioeconomic and ethnic groups. Risk factors such as hypertension, diabetes, and obesity increased most rapidly among younger people between 12 to 50 years of age.
Researchers from the Coriell Institute for Medical Research and the National Human Genome Research Institute (NHGRI) have announced the discovery of five sites of variation in the genome that are associated with blood pressure in African Americans.
Genentech, Inc. announced that an international Phase III study demonstrated that oral Xeloda® plus oxaliplatin (XELOX) is superior to a commonly used intravenous chemotherapy, 5-FU/LV (infused 5-fluorouracil plus leucovorin), in increasing the time people with adjuvant colon cancer lived without their cancer returning when given immediately after surgery. The data show those who participated in the study and took XELOX immediately after surgery lived longer without their cancer being detectable than those who took intravenous 5U/LV. No new adverse events related to Xeloda were observed in the study.
Jeff Kepner, the nation"s first bilateral hand transplant recipient, spoke at a news conference today about his surgery and showed the progress he has made since the May 4 procedure. Mr. Kepner, who lost both hands and feet following a bacterial infection in 1999, is the second patient to be treated with the "Pittsburgh Protocol," a new immune modulation therapy that aims to reduce the risk associated with toxic anti-rejection drugs.
King Saud University professor, Dr. Adel Almogren, along with a diverse team of academic researchers from the United States, Canada, and Taiwan, has discovered a new process that could lead to a vaccine to block cancer cell adhesion and growth.
Zimmer Holdings, Inc. (NYSE: ZMH; SWX: ZMH) announced that data from a comparative clinical study conducted by researchers at the Mayo Clinic and the Joint Replacement Surgeons of the Indiana Research Foundation describes the low stiffness and osteoconductive properties of Zimmer"s Trabecular Metal Technology. The study, published in The Journal of Arthroplasty, found significant reductions in acetabular bone loss adjacent to the Trabecular Metal device compared to the titanium component, and a significant relative increase in bone mineral density (BMD) after total hip arthroplasty (THA) using implants made with Zimmer"s proprietary Trabecular Metal Technology.
Many countries worldwide are digitizing patients" medical records. In the
Scientists have a better understanding of what causes an abnormal number of chromosomes in offspring, a condition called aneuploidy that encompasses the most common genetic disorders in humans, such as Down syndrome, and is a leading cause of pregnancy loss.