Popular Articles

Pharmaceutical Companies Are Ready For The H1N1 Influenza Pandemic
Commenting on the World Health Organisation"s decision to raise its global pandemic alert level to Phase 6 due to the global spread of the novel H1N1 influenza strain, Acting Director General Michael D. Boyd of the International Federation of Pharmaceutical Manufacturers and Associations (IFPMA), of which the Irish Pharmaceutical Healthcare Association (IPHA) is a member, said:
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Fruitfly Model Of A Neuropathic Disease Demonstrates Novel Role For Proteins In The Family Of ATyr Pharma's Product Class
Research published in the June 26, 2009 edition of Proceedings of National Academy of Sciences provides further evidence for novel roles of tRNA synthetases in disease, validating the therapeutic potential for aTyr Pharma"s new class of naturally occurring protein agents. The aminoacyl tRNA synthetases are universal and essential components of protein synthesis machinery found in all organisms, but human synthetases have naturally occurring resected variants with potent cell signaling activities that are vital to normal functioning of humans. aTyr Pharma"s proprietary product generating engine consists of these resected proteins (resectins) of human aminoacyl tRNA synthetases with cell signaling activities distinct from the protein synthesis activities. In this recently published study, a model of a human neuropathy was created in the fruit fly (Drosophila) by introducing mutations in the tyrosyl-tRNA synthetase which correspond to disease associated mutations in humans. These dominant mutations do not cause a loss in the protein synthesis activity, indicating that the neuropathy arises from distinct activities of this tRNA synthetase. This work provides further proof of noncanonical roles for tRNA synthetases in human disease.
News of the day
Number Of Abortion Procedures Continues To Decline In Minnesota And Wisconsin
The following summarizes news coverage of state abortion statistics in Minnesota and Wisconsin.~ Minnesota: The number of abortions performed in Minnesota decreased for the second consecutive year in 2008, according to an annual report from the state Department of Health, the Minneapolis Star Tribune reports. Except for a one-time increase in 2006, the number of abortions in Minnesota has trended downward since a peak in 1980, when 19,028 procedures were performed. The new report found that 12,948 abortions were performed in the state in 2008, a decrease of 895 from 2007. Women ages 20 to 24 accounted for about one-third of the procedures, the most among any age group. The number of procedures among teenagers continued a decline that began in the 1990s but had leveled off slightly earlier this decade, the report found. The report also found that less than one-third of women reported using contraception and about one in seven was married at the time of conception (Von Sternberg, Minneapolis Star Tribune, 7/1).~ Wisconsin: Wisconsin abortion providers performed 8,229 procedures in 2008, the lowest number since the state began collecting statistics in 1974, according to an annual report by the state Department of Health Services, the AP/Milwaukee Journal-Sentinel reports. The number of abortions has declined annually since 2003, when 10,557 procedures were performed. State law requires abortion providers to provide DHS with the data. According to the report, slightly more than half of abortions took place in the first eight weeks of pregnancy. Women who had never been married accounted for about three-fourths of all procedures. The report found that 12% of abortions occurred among women ages 35 and older; 34% were among women ages 20 to 24; 11% were among women ages 18 and 19; and 6% were among girls ages 15 to 17. The number of abortions among minors decreased from 551 in 2007 to 500 in 2008, with parents providing consent in 452 of those cases (Richmond, AP/Milwaukee Journal-Sentinel, 6/30).
Nutrition

World Food Programme Calls For Urgent Action On Global Hunger And Humanitarian Needs

The Executive Director of the United Nations World Food Programme (WFP), Josette Sheeran, has urged G8 Development Ministers meeting today in Italy, to remember the needs of the world"s hungriest people and continue to support WFP, which depends entirely on voluntary donations. "We must not forget the urgent hunger needs around the world, or cut back on support for hungry people. The world"s most vulnerable are being hit by the combined effects of the global financial downturn and stubbornly high food prices in many developing world markets. Hunger can lead to dangerous destabilisation, and impact global peace and security." "With one in six people going hungry, one child dying every six seconds, and 80 per cent of Sub-Saharan African countries facing higher food prices than a year ago, the poor and the hungry are facing one of the biggest crises in our lifetimes. It is critical for the world to remember that hunger will have a permanent impact on children and we may lose a generation unless they have adequate access to nutrition during this crisis." "We support the efforts of the United Nations Food and Agriculture Organization (FAO), and the International Fund for Agricultural Development (IFAD) to double global food production by 2050. At the same time we must remember, as the Nobel laureate and eminent economist, Amartya Sen has said, famine is an issue of food access for individuals. Without food, people revolt, migrate, or die. None of these are acceptable options." "After the Great Depression, the world created institutions, including World Food Programme, which should expand - not contract - when times are bad. Global food aid is at a 20 year low and we must meet urgent needs to avoid an unprecedented humanitarian crisis. At this moment of dramatically growing need, it would be wrong to cut our funding. We have proven our ability to scale up when the world calls on us and equips us with the means to do so. We have also shown that we can do this in a way that supports recipient nations" own long term development strategies to tackle hunger." World Food Programme


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