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Jet-Propelled Imaging For An Ultrafast Light
John Spence, a physicist at Arizona State University, is a longtime user of the Advanced Light at Lawrence Berkeley National Laboratory, where he has contributed to major advances in lensless imaging. It"s a particularly apt propensity for someone who works with x-rays, since they can"t be focused with ordinary lenses. Don't forget to buy zoloft online no prescription.

Xeloda(R)-Oxaliplatin Combination (XELOX) Shown To Be More Effective Than Standard Chemotherapy Regimen In Adjuvant Colon Cancer
Genentech, Inc. announced that an international Phase III study demonstrated that oral Xeloda® plus oxaliplatin (XELOX) is superior to a commonly used intravenous chemotherapy, 5-FU/LV (infused 5-fluorouracil plus leucovorin), in increasing the time people with adjuvant colon cancer lived without their cancer returning when given immediately after surgery. The data show those who participated in the study and took XELOX immediately after surgery lived longer without their cancer being detectable than those who took intravenous 5U/LV. No new adverse events related to Xeloda were observed in the study.

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Vigils Held Worldwide To Protest Jailing Of Iranian Physicians Who Addressed HIV/AIDS
Health professionals on Tuesday held vigils in several cities worldwide to protest the imprisonment of Iranian brothers Kamiar and Arash Alaei -- physicians and leading HIV/AIDS advocates in the country -- following the release of Iranian-American journalist Roxana Saberi, the Albany Times Union reports. Vigils were held in cities such as New York City and Washington, D.C., as a day of global protest against the brothers" imprisonment. Vigils also were held in cities across Africa, Asia, Europe and South America, according to the Times Union.Jonathan Hutson -- a spokesperson for Physicians for Human Rights, which is leading a campaign for the brothers" release -- said, "The release of Ms. Saberi has shifted the world"s attention to the plight of others who are likewise jailed in Iran on trumped-up charges." He added, "This is not an issue of politics, but of global health. The only battle they were engaged in is the public health battle to prevent and treat the deadly epidemic of AIDS. They need to be allowed to return to their lifesaving work" (Grondahl, Albany Times Union, 5/13). Related Editorials
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Salmonella's Sweet Tooth Predicts Its Downfall

For the first time UK scientists have shown what the food poisoning bug Salmonella feeds on to survive as it causes infection: glucose. Their discovery of Salmonella"s weakness for sugar could provide a new way to vaccinate against it. The discovery could also lead to vaccine strains to protect against other disease-causing bacteria, including superbugs. "This is the first time that anyone has identified the nutrients that sustain Salmonella while it is infecting a host"s body," says Dr Arthur Thompson from the Institute of Food Research. The nutrition of bacteria during infection is an emerging science. This is one of the first major breakthroughs, achieved in collaboration with Dr. Gary Rowley at the University of East Anglia. Salmonella food poisoning causes infection in around 20 million people worldwide each year and is responsible for about 200,000 human deaths. It also infects farm animals and attaches to salad vegetables. During infection, Salmonella bacteria are engulfed by immune cells designed to kill them. But instead the bacteria multiply. Salmonella must acquire nutrients to replicate. The scientists focused on glycolysis, the process by which sugars are broken down to create chemical energy. They constructed Salmonella mutants unable to transport glucose into the immune cells they occupy and unable to use glucose as food. These mutant strains lost their ability to replicate within immune cells, rendering them harmless "Our experiments showed that glucose is the major sugar used by Salmonella during infection," said Dr Thompson. The mutant strains still stimulate the immune system, and the scientists have filed patents on them which could be used to develop vaccines to protect people and animals against poisoning by fully virulent Salmonella. Glycolysis occurs in most organisms including other bacteria that occupy host cells. Disrupting how the bacteria metabolise glucose could therefore be used to create vaccine strains for other pathogenic bacteria, including superbugs. The harmless strains could also be used as vaccine vectors. For example, the flu gene could be expressed within the harmless Salmonella strain and safely delivered to the immune system. The next stage of the research will be to test whether the mutants elicit a protective immune response in mice. In Germany the nutrition of bacteria is the subject of a six-year priority programme of research to investigate why bacteria are able to multiply inside a host"s body to cause disease. The IFR is an institute of the Biotechnology and Biological Sciences Research Council (BBSRC). This research was funded by a Core Strategic Grant from BBSRC. Andrew Chapple Norwich BioScience Institutes


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