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Opinion: Boston Globe Columnist Examines Arguments Against DDT Use In Uganda
Boston Globe columnist Derrick Jackson examines why some Ugandans do not support indoor spraying of DDT to prevent malaria. Grace Kagoro, a biology professor and environmental researcher at Mbarara University of Science and Technology, is "nervous about adding what she said could be one more shock to the soil and water," according to Jackson.
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Study Suggests Preseason Shoulder Strength May Determine Injury Severity For Baseball Pitchers
Athletic injuries can derail any player"s ability to compete, but for a baseball pitcher his shoulder strength and control is critical. A new study to be presented at the American Orthopaedic Society for Sports Medicine"s (AOSSM) Annual Meeting in Keystone, Colorado, suggests that testing a pitcher"s shoulder strength through a series of exercises during the preseason may help create a focused strength training program to prevent serious injury during the season.
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Girl Scouts Can Be Good Venue For Physical Activity
Promoting physical activity during Girl Scout meetings can be an effective way for young girls to get the exercise they need to be healthy, according to a study presented at the American College of Sports Medicine"s 56th Annual Meeting in Seattle.
Cardiovascular

'SIRT'ain Security: The Protein SIRT3 Protects The Heart

Sirtuin proteins have been shown to promote longevity in many organisms, and increased expression of one sirtuin protein, SIRT3, has been linked to increased human lifespan. New data, generated in mice, by Mahesh Gupta and colleagues, at the University of Chicago, Chicago, has revealed that Sirt3 helps protect the mouse heart. In the study, the heart of mice lacking Sirt3 was found to show signs of becoming enlarged (a process known as cardiac hypertrophy), at about 8 weeks of age. Further, these mice responded dramatically to conditions that induce cardiac hypertrophy, whereas mice overexpressing Sirt3 were protected from cardiac hypertrophy under the same conditions. Additional analysis revealed the mechanism by which Sirt3 blocks the cardiac hypertrophic response, thereby providing protection to the mouse heart. Specifically, it acts in heart muscle cells via the protein Foxo3a to increase expression of anti-oxidant proteins, thereby reducing levels of damaging oxidants. TITLE: Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice AUTHOR: Mahesh P. Gupta University of Chicago, Chicago, Illinois, USA. PDF of this article Karen Honey Journal of Clinical Investigation


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