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Link Between Successful Weight Loss And Vitamin D Levels
Vitamin D levels in the body at the start of a low-calorie diet predict weight loss success, a new study found. The results, which suggest a possible role for vitamin D in weight loss, were presented at The Endocrine Society"s 91st Annual Meeting in Washington, D.C.
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Stanford Bioethicist And Colleagues Call For Federal Regulation Of Genetic Ancestry Testing
Imagine donating a sample of your DNA to help researchers study the genetics of diabetes. The disease is common among your friends and family, and you"re proud of your role in finding out why. Now, imagine that some time later, you learn that your DNA has been used for other studies on topics you never expected - schizophrenia, human migration, inbreeding. Although your name isn"t attached to the sample anymore, scientists are using your DNA to draw conclusions about your community and your ancestors. Some of these studies violate your cultural beliefs.
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Summer's Here: HSE Won't Rain On Your Paradẹ€¦or Your Fete!
If you believe everything you read, "health and safety" is to blame for a lot of fun events being cancelled. Plastic duck races, ice cream toppings and even Morris Dancing have all allegedly fallen victim to excessive health and safety regulations.
Cardiovascular

'SIRT'ain Security: The Protein SIRT3 Protects The Heart

Sirtuin proteins have been shown to promote longevity in many organisms, and increased expression of one sirtuin protein, SIRT3, has been linked to increased human lifespan. New data, generated in mice, by Mahesh Gupta and colleagues, at the University of Chicago, Chicago, has revealed that Sirt3 helps protect the mouse heart. In the study, the heart of mice lacking Sirt3 was found to show signs of becoming enlarged (a process known as cardiac hypertrophy), at about 8 weeks of age. Further, these mice responded dramatically to conditions that induce cardiac hypertrophy, whereas mice overexpressing Sirt3 were protected from cardiac hypertrophy under the same conditions. Additional analysis revealed the mechanism by which Sirt3 blocks the cardiac hypertrophic response, thereby providing protection to the mouse heart. Specifically, it acts in heart muscle cells via the protein Foxo3a to increase expression of anti-oxidant proteins, thereby reducing levels of damaging oxidants. TITLE: Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice AUTHOR: Mahesh P. Gupta University of Chicago, Chicago, Illinois, USA. PDF of this article Karen Honey Journal of Clinical Investigation


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