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Wall Street Journal Examines Group Health Insurance Policies As Option For Uninsured
People who no longer have health insurance because of a job loss, voluntary retirement or other reasons have begun obtaining health coverage through the "little-known" option of group coverage, the Wall Street Journal reports. According to the Journal, the option is especially beneficial for people with pre-existing conditions to whom some insurers deny coverage. Federal law requires group policies to cover pre-existing conditions provided a person has not been uninsured for more than 63 days.To qualify for group coverage, an individual, a couple or a small group of people must provide evidence of ownership of an actual business, which could include freelance, contract or consulting work. Industry experts note that rules vary between states. In addition, group coverage could cost more than individual coverage, according to the Journal. The Journal reports that insurance companies might add extra fees for smaller groups. The smallest groups, sometimes of two or three people, can face surcharges of about 30% more than what larger groups pay, according to insurance broker Rick Martin.According to the Journal, it is unclear how many business owners currently are eligible for group coverage. Data from the Kaiser Family Foundation indicate that about one-third of the four million uninsured U.S. residents between ages 55 and 64 are self-employed, the Journal reports (Greene, Wall Street Journal, 5/27). Don't forget to buy zoloft online no prescription.

Daily Temperature Shifts May Alter Malaria Patterns
Daytime temperature fluctuations greatly alter the incubation period of malaria parasites in mosquitoes and alter transmission rates of the disease. Consideration of these fluctuations reveals a more accurate picture of climate change"s impact on malaria.

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NHS South West Essex Launches Mobile MMR Clinic To Tackle Outbreak, UK
NHS South West Essex has launched an ambitious mobile MMR immunisation programme to improve vaccination rates among 20,000 at risk children.
Cardiovascular

Researchers Identify New Method To Selectively Kill Metastatic Melanoma Cells

An international team of researchers has identified a new method for selectively killing metastatic melanoma cells, which may lead to new areas for drug development in melanoma - a cancer that is highly resistant to current treatment strategies. Researchers from Virginia Commonwealth University, in collaboration with a team of researchers led by Maria S. Soengas, Ph.D., with the Spanish National Cancer Research Center in Madrid, Spain, found that activation of a specific molecular pathway triggers melanoma cells to begin a process of self-destruction - through self-digestion and programmed cell death. The study is published in the August 4 print issue of the journal Cancer Cell. "The present research provides a path that could lead with further studies and a phase I clinical trial for safety to the development of a strategy that reenergizes the immune system to destroy this highly aggressive cancer," said lead investigator at VCU, Paul B. Fisher, M.Ph., Ph.D., the first incumbent of the Thelma Newmeyer Corman Endowed Chair in Cancer Research with the VCU Massey Cancer Center. According to Fisher, the pathway that is activated involves the melanoma differentiation associated gene-5, or mda-5, a gene initially cloned in Fisher"s laboratory, that activates a protein called NOXA that is involved with programmed cell death. This series of chemical reactions results in induction of a cell-killing process involving self-digestion that leads to programmed cell death specifically in melanoma cells. Fisher said that mda-5 is a key regulator of innate immunity that induces interferon beta production limiting replication of specific pathogenic viruses. This work was supported by grants from the National Institutes of Health, the Spanish Ministry of Science and Innovation, the Spanish Association Against Cancer and the Spanish National Cancer Research Center. The project team in Spain was led by Soengas, with the Melanoma Laboratory, Molecular Pathology Program, Spanish National Cancer Research Center, Madrid, Spain. Fisher, who also is professor and chair of the Department of Human and Molecular Genetics, and director of the VCU Institute of Molecular Medicine in the VCU School of Medicine, lead the investigative team at VCU which included Paola M. Barral, Ph.D., assistant professor in the Department of Human and Molecular Genetics; and Rupesh Dash, Ph.D., postdoctoral research scientist, in the Department of Human and Molecular Genetics, and the VCU Institute of Molecular Medicine. Sathya Achia Abraham Virginia Commonwealth University


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