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UNICEF: Children And Women Displaced By Conflict In Pakistan Need Urgent And Ongoing Support
UNICEF is deeply concerned about the condition of thousands of children who have been displaced by conflict, or who remain in affected areas, in north-western Pakistan. Nearly 50 per cent of the estimated 2 million displaced are children, many of whom are in urgent need of health and educational services, nutritional support, access to clean water and sanitation as well as protection. Their situation has been compounded by the harsh summer temperatures. Don't forget to buy zoloft online no prescription.

House, Senate Committees Approve Bills That Include Influenza Pandemic Funds
The Senate Appropriations Committee on Thursday voted unanimously to approve a $91.3 billion defense and foreign aid spending bill that includes President Obama"s request for $1.5 billion in emergency funds to fight a potential influenza pandemic, the AP/Winston-Salem Journal reports. The House version of the bill, approved Thursday in a 368-60 vote, adds $500 million to the pandemic preparedness funds (AP/Winston-Salem Journal, 5/15). Last month, the public health emergency involving the H1N1 influenza virus spurred congressional lawmakers to rethink the elimination of $870 million from the economic stimulus package that would have been used to combat an influenza pandemic. Democratic legislators eliminated the funds in order to garner support from congressional Republicans to pass the stimulus package (Kaiser Daily Health Policy Report, 4/28).

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Likelihood Of Having Breast And Cervical Screening Associated To Wealth And Ethnicity
A research published today on bmj.com reports that Caucasian British women are more likely to have had a mammogram. And there is more probability that women owning cars or homes have had a mammogram.
Public Health

Novel Findings Presented By Pitt Melanoma Researchers At ASCO

Researchers from the University of Pittsburgh Cancer Institute (UPCI) have identified eight genes that help predict a melanoma patient"s response to treatment. The new findings are being presented at the 45th annual meeting of the American Society of Clinical Oncology (ASCO), May 29 to June 2, in Orlando, Fla. "Approximately 70,000 people will be diagnosed with metastatic melanoma this year," said principal investigator Hussein Tawbi, M.D., M.Sc., assistant professor of medicine, University of Pittsburgh School of Medicine, and with UPCI"s Melanoma Program. "This form of cancer is aggressive and often resistant to chemotherapy. In fact, only 7 to 10 percent of patients are likely to respond to the current standard of care. We wanted to see if there was a way to predict which patients would respond to treatment and which ones would not." Dr. Tawbi and his colleagues examined the tumor tissues of 21 patients with metastatic melanoma, some of whom responded to chemotherapy and some who did not. Once the cases were divided, the researchers used a mathematical tool called Neural Network Analysis to survey over 25,000 genes and the regulators that turn the genes on and off to see if they could identify ones that could distinguish responders from nonresponders. "Cancer cells contain massive amounts of information that, if analyzed appropriately, may inform us how to kill them," said Dr. Tawbi. "They contain thousands of genes, and every gene has a switch that turns it on or off. Neural Network Analysis, which utilizes pattern recognition algorithms, helped us identify a signature of eight genes and their switches that predict a patient"s likelihood of responding to treatment for metastatic melanoma." The results of this study are being validated in a larger sample of 80 patients. Genetic testing could someday allow doctors to identify which patients will respond to standard chemotherapy and which patients won"t, leading to improved treatments for both groups. "The genes that we isolated in this study could be potential targets for new therapies down the road," explained Dr. Tawbi. "We need to find options for the large number of patients with metastatic disease who won"t respond to existing treatments. This work takes us one step closer to doing so." The study was funded by the Eastern Cooperative Oncology Group and the University of Pittsburgh Cancer Institute. Courtney McCrimmon University of Pittsburgh Schools of the Health Sciences


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