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CuraGen Announces Expansion Of CR011-vcMMAE Phase II Trial In Advanced Breast Cancer
CuraGen Corporation (Nasdaq: CRGN) announced that its Phase I/II Trial evaluating CR011-vcMMAE for the treatment of patients with advanced breast cancer has met the efficacy criteria for advancement to the second stage of enrollment. To date, 29 patients have been enrolled in this trial, including 15 in the Phase II portion. Two of the first four evaluable Phase II patients were progression-free at 12 weeks, therefore, as part of the Simon 2-Stage design, the Phase II trial will now advance to the second stage and enroll a total of approximately 25 patients. The principal investigator of the study is Dr. Linda Vahdat, Medical Director of the Breast Cancer Research Program and Associate Professor of Clinical Medicine, /Weill Cornell. CuraGen anticipates presenting updated results from this study during the second half of 2009. Don't forget to buy zoloft online no prescription.

Supreme Court Nominees Should Disclose Views On Constitutional Issues, USA Today Opinion Piece States
One thing that "has been conspicuously absent" from the confirmation hearings for Supreme Court nominee Sonia Sotomayor is "substance," Jonathan Turley, the Shapiro Professor of Public Interest Law at George Washington University, writes in a USA Today opinion piece. According to Turley, "The vast majority of questions and answers remained on a shallow and predictable level where Sotomayor did little more than describe current doctrines and case law -- avoiding disclosures of her own views." He continues, "What is most striking is how Sotomayor"s statements were virtually identical to both her conservative and liberal predecessors," including her comments that Roe v. Wade and Planned Parenthood v. Casey are "the precedent of the court."Turley writes, "The content-light character in these hearings is largely the product of the "Ginsburg rule" -- named after Justice Ruth Bader Ginsburg, who refused to answer questions in her 1993 confirmation hearing about any case or matter upon which she might later vote." According to Turley, "Later nominees for both parties have relied on the Ginsburg rule to turn the hearings into prolonged photo-ops for senators, who largely ask wafer-thin questions to solicit largely scripted answers." The rule "allows nominees to get by with meaningless sound bites that promise to respect precedent, the Framers [of the Constitution] and collegiality in general," he adds. Furthermore, it "tells the public nothing about a nominee"s philosophy or purpose before giving her life tenure on the world"s most powerful court," Turley writes.According to Turley, there is a "simple solution to returning substance to the confirmation process: End the Ginsburg rule by insisting that nominees answer questions about their specific views on constitutional rights." Although "the current system works well for presidents, nominees and senators," it "does little for the public or the system of justice," he writes (Turley, USA Today, 7/16).

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HCL Welcomes Government Proposals For More Flexible NHS, UK
HCL plc, the UK"s largest health and social care recruitment agency, said the Government"s proposals to reform the NHS by devolving power to frontline professionals and patients will mean a greater need for flexible staffing and more collaboration between the public and private sectors.
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New Training And Education Programme Introduced For The Scientific Workforce In Genetics, UK

A new education programme has been developed to provide enhanced training in genetic technologies and clinical applications for healthcare scientists working in laboratory genetics, Health Minister Ann Keen announced. This pilot is part of the UK Modernising Scientific Careers (MSC) programme which is transforming education, training and career pathways for the healthcare science workforce. The pilot funded by the Department of Health is investing over ÷£4.5 million to address the training needs of the healthcare science workforce in genetics. The new pilot will: - Respond to future workforce needs, which has increased significantly in the last ten years as scientific discoveries have created new opportunities to diagnose and predict disease; - Inform the roll out of the MSC programme for other healthcare science training programmes which will begin in 2010 with full implementation in 2012; - Establish a national School of Genetics in the West Midlands; and - Modernise the genetics curricula to respond to breakthrough scientific advances and their applications for patients and the public. Health Minister Ann Keen said: "Science and innovation are at the heart of high quality healthcare for patients in the 21st century, underpinning the development of new diagnostics and treatments which have a major impact on the health and social care system. "Geneticists carry out life informing work by predicting and diagnosing disease so it is fundamental that we invest in creating training and career opportunities for this important group of NHS staff". "This pilot will also inform the Modernising Scientific Careers programme as it moves to implementation as well as creating a high quality healthcare science workforce which will make the benefits of science and technology a reality for patients." Professor Sue Hill, Chief Scientific Officer for the Department of Health said: "This will give trainees modernised education and training focussed on the advances in genetic technology and knowledge to ensure delivery of leading edge services for patients and the public. It also supports the delivery of the NHS Next Stage Review commitments putting high quality care, innovation and improved productivity at its core in this fast-moving field. "I look forward to working with those involved in the pilot and to consulting with MSC stakeholders as it progresses." Peter Blythin, Director of Nursing and Workforce at NHS West Midlands said: "We are delighted to be hosting and establishing a national School of Genetics here in the West Midlands and to be part of such a groundbreaking pilot scheme that will ultimately deliver leading edge services for patients and the public." The pilot programme, to begin in October 2009, will fund 24 pilot training posts for 12 trainee Healthcare Science Practitioners and 12 Healthcare Scientists in Genetics. The trainees will be based in a number of NHS genetics departments throughout England and will be brought together for national training events and courses. NHS West Midlands has agreed to host the process for all the SHAs involved. Department of Health, UK


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