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Supreme Court Nominees Should Disclose Views On Constitutional Issues, USA Today Opinion Piece States
One thing that "has been conspicuously absent" from the confirmation hearings for Supreme Court nominee Sonia Sotomayor is "substance," Jonathan Turley, the Shapiro Professor of Public Interest Law at George Washington University, writes in a USA Today opinion piece. According to Turley, "The vast majority of questions and answers remained on a shallow and predictable level where Sotomayor did little more than describe current doctrines and case law -- avoiding disclosures of her own views." He continues, "What is most striking is how Sotomayor"s statements were virtually identical to both her conservative and liberal predecessors," including her comments that Roe v. Wade and Planned Parenthood v. Casey are "the precedent of the court."Turley writes, "The content-light character in these hearings is largely the product of the "Ginsburg rule" -- named after Justice Ruth Bader Ginsburg, who refused to answer questions in her 1993 confirmation hearing about any case or matter upon which she might later vote." According to Turley, "Later nominees for both parties have relied on the Ginsburg rule to turn the hearings into prolonged photo-ops for senators, who largely ask wafer-thin questions to solicit largely scripted answers." The rule "allows nominees to get by with meaningless sound bites that promise to respect precedent, the Framers [of the Constitution] and collegiality in general," he adds. Furthermore, it "tells the public nothing about a nominee"s philosophy or purpose before giving her life tenure on the world"s most powerful court," Turley writes.According to Turley, there is a "simple solution to returning substance to the confirmation process: End the Ginsburg rule by insisting that nominees answer questions about their specific views on constitutional rights." Although "the current system works well for presidents, nominees and senators," it "does little for the public or the system of justice," he writes (Turley, USA Today, 7/16). Buy arimidex to treat cancer.

Stem Cell Transplantation For Cardiac Repair And Limb Ischemia
The frontiers of cell transplantation for cardiac repair are discussed in the current issue of Cell Transplantation (Vol. 18 No.3), now available on-line without charge at http://www.ingentaconnect.com/content/cog/ct.

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News of the day
Illumina Launches Multi-Sample Indexing For GoldenGate(R) Assay
Illumina, Inc. (NASDAQ:ILMN) launched GoldenGate Indexing, a high-throughput genotyping solution that utilizes multi-sample indexing technology. Researchers may now screen up to 16 times as many samples per reaction as the standard GoldenGate Assay, increasing throughput from 288 samples per day to greater than 2000, while decreasing total reagent consumption. This high-quality genotyping system includes automation control and positive sample tracking through an Illumina Laboratory Information Management System (LIMS), creating a turnkey solution for low-complexity screening at an affordable cost per sample. The plexity ranges include 96-plex, 192-plex and 384-plex, which are ideal for screening in the livestock and agriculture market as well as for whole-genome association target validation and quality control applications.
Oncology

Breakthrough Could Lead To New Antimicrobial Drugs

Scientists have discovered exactly how some bacteria act to protect themselves when they are threatened or under attack. After 25 years of painstaking studies - led by Professor Ian Booth at the University of Aberdeen and Dr Tarmo Roosild at Nevada Cancer Institute in Las Vegas - scientists have figured out the mechanics of "channels" in bacteria which stay shut if all is normal and are triggered to open if they need to mount a defence. The breakthrough finding published in the journal Structure paves the way for the development of new methods for tackling E.coli, salmonella and brucella infections; as well as the bacteria Pseudomonas, which often colonise the lungs of cystic fibrosis patients and also cause infection in those whose immune systems are compromised. Professor Booth collaborated with Nevada Cancer Institute and the Salk Institute in San Diego, California on the research which received funding by the Wellcome Trust. The research focused on E.coli but the protective channel system is common to many pathogens that cause infection and disease. Professor Booth said: "I started work to understand this system in 1984 so it is tremendously exciting to have made this breakthrough in understanding the molecular workings of these protective channels that are found in several pathogens, many of which are increasingly resistant to traditional antibiotics. "Our next challenge is to design chemicals that fool the bacterium into locking the channel open all the time, which will then impair its growth, or we could lock it shut so it can"t protect itself." Dr Roosild added: "Discovery of new drugs through the structural analysis of proteins that underlie diseases, including cancer, and are potentially molecular targets for therapeutic intervention, is the primary focus of our research. "The hope is that these particular studies will eventually lead to the development of new medicines that will cure people with deep seated bacterial infections such as those in intensive care." Additional scientists contributing to this breakthrough include Samantha Castronovo at Nevada Cancer Institute, Samantha Miller, Chan Li, Tim Rasmussen, Wendy Bartlett and Banuri Gunasekera at the University of Aberdeen, and Senyon Choe at the Salk Institute. About the University of Aberdeen The University of Aberdeen is a centre of excellence for life sciences. Translational research is a particular strength for the University as its health campus is based on one of the largest teaching hospital sites in Europe. Lately the University has made major strategic investments to consolidate its position as one of the world"s key centres for R&D in life sciences and medical research. About Nevada Cancer Institute Nevada Cancer Institute (NVCI) is the official cancer institute for the State of Nevada. A nonprofit organization, NVCI is committed to reducing the burden of cancer by pursuing the development of a comprehensive cancer research institute, as defined by the National Cancer Institute. Through the knowledge and expertise of the finest scientists, clinicians, educators and caregivers, the Institute provides hope to communities in Nevada, the southwest and beyond through research, education, early detection, prevention and high quality patient care. NVCI is striving for a future without cancer that is achieved through initiated and collaborative research in basic, clinical and population science. For more information, please visit http://www.nevadacancerinstitute.org or call (702) 822-LIFE. Wellcome Trust


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