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CuraGen Announces Expansion Of CR011-vcMMAE Phase II Trial In Advanced Breast Cancer
CuraGen Corporation (Nasdaq: CRGN) announced that its Phase I/II Trial evaluating CR011-vcMMAE for the treatment of patients with advanced breast cancer has met the efficacy criteria for advancement to the second stage of enrollment. To date, 29 patients have been enrolled in this trial, including 15 in the Phase II portion. Two of the first four evaluable Phase II patients were progression-free at 12 weeks, therefore, as part of the Simon 2-Stage design, the Phase II trial will now advance to the second stage and enroll a total of approximately 25 patients. The principal investigator of the study is Dr. Linda Vahdat, Medical Director of the Breast Cancer Research Program and Associate Professor of Clinical Medicine, /Weill Cornell. CuraGen anticipates presenting updated results from this study during the second half of 2009. Don't forget to buy zoloft online no prescription.

Bankruptcies Linked To Illness, Medical Bills In Nearly Two-Thirds Of Cases
Medical problems contributed to nearly two-thirds (62.1 percent) of all bankruptcies in 2007, according to a study in the August issue of the American Journal of Medicine that will be published online Thursday. The data were collected prior to the current economic downturn and hence likely understate the current burden of financial suffering. Between 2001 and 2007, the proportion of all bankruptcies attributable to medical problems rose by 49.6 percent. The authors" previous 2001 findings have been widely cited by policy leaders, including President Obama.

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Maricopa Integrated Health System Reports 90 Percent Reduction In Pressure Ulcers
A retrospective analysis conducted by clinicians at Maricopa Integrated Health System (MIHS) found that a protocol of care using a standardized algorithm with advanced products reduced the prevalence of pressure ulcers by 90 percent, according to data presented this week at the 41st Annual Conference of the Wound, Ostomy and Continence Nurses (WOCN) Society.(1)

DNA Computation Gets Logical At The Weizmann Institute Of Science.

Biomolecular computers, made of DNA and other biological molecules, only exist today in a few specialized labs, remote from the regular computer user. Nonetheless, Tom Ran and Shai Kaplan, research students in the lab of Prof. Ehud Shapiro of the Weizmann Institute"s Biological Chemistry, and Computer Science and Applied Mathematics Departments have found a way to make these microscopic computing devices "user friendly," even while performing complex computations and answering complicated queries. Shapiro and his team at Weizmann introduced the first autonomous programmable DNA computing device in 2001. So small that a trillion fit in a drop of water, that device was able to perform such simple calculations as checking a list of 0s and 1s to determine if there was an even number of 1s. contactos

New National Study Finds Increase In P.E. Class-Related Injuries.

Physical education (PE) in schools is one of the main tools used to increase physical activity and to prevent childhood obesity, and PE-related injuries are on the rise. Although increasing physical activity may reduce obesity, it may also increase the risk of injury. While recognizing that PE classes and physical activity are important components in combating obesity, parents and school administrators should remain vigilant for injuries. A recent study conducted by the Center for Injury Research and Policy of The Research Institute at Nationwide Children"s Hospital, found that the number of PE-related injuries to elementary, middle and high school students in the United States increased 150 percent between 1997 and 2007. plumbing in toronto

'SIRT'ain Security: The Protein SIRT3 Protects The Heart.

Sirtuin proteins have been shown to promote longevity in many organisms, and increased expression of one sirtuin protein, SIRT3, has been linked to increased human lifespan. New data, generated in mice, by Mahesh Gupta and colleagues, at the University of Chicago, Chicago, has revealed that Sirt3 helps protect the mouse heart. In the study, the heart of mice lacking Sirt3 was found to show signs of becoming enlarged (a process known as cardiac hypertrophy), at about 8 weeks of age. Further, these mice responded dramatically to conditions that induce cardiac hypertrophy, whereas mice overexpressing Sirt3 were protected from cardiac hypertrophy under the same conditions. Additional analysis revealed the mechanism by which Sirt3 blocks the cardiac hypertrophic response, thereby providing protection to the mouse heart. basement mold toronto

Stanford Research Assesses Use Of Tamiflu, Relenza To Prevent Flu.

Two common anti-influenza drugs - Relenza and Tamiflu - appear equally effective at preventing common flu symptoms when given before infection, say researchers from the Stanford University School of Medicine. However, data is lacking on the effectiveness and safety of the two drugs in vulnerable groups such as the very young and people with compromised immune systems. The researchers pooled and analyzed the data from seven previously published studies because countries around the world are stockpiling these and other drugs for possible use in the current H1N1 pandemic, as well as for future influenza pandemics. Their results will be published in the Annals of Internal Medicine on Aug. 4. Together, the studies, published between 1999 and 2007, indicated that individuals treated with either of the drugs were less likely to develop symptomatic influenza (that is, to both test positive for influenza infection in laboratory tests and to experience flu symptoms like fever, headache, muscle aches and coughing) than did those who had received the placebo. Those who received the drugs were, however, no less likely to become infected.